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March 1, 2000CarcinogenesisOpen Access

Apoptosis in cancer

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Authors

Scott W. Lowe
Scott W. LoweOntario Institute for Cancer ResearchALAthena W. LinRoswell Park Comprehensive Cancer Center

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Lowe et al. (2000) studied this question.

synapsesocial.com/papers/6a819ee4933117ee297765ddhttps://doi.org/10.1093/carcin/21.3.485
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mutations in the gene encoding the adenovirus early region 1B 19,000-molecular-weight tumor antigen cause the degradation of chromosomal DNA1984 · 156 citations
  2. 2Apoptosis in the Pathogenesis and Treatment of Disease1995 · 6,582 citations
  3. 3bax -deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis1997 · 370 citations
  4. 4Apaf1 (CED-4 Homolog) Regulates Programmed Cell Death in Mammalian Development1998 · 902 citations
  5. 5The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins.1992 · 667 citations