Key result
Continuous intravenous aspart insulin and a specialized diet reduced triglyceride levels by 82% at 96 hours and prevented pancreatitis recurrence over 12 months in an 11-year-old girl.
Why the study?
Severe hypertriglyceridemia in children is rare but associated with recurrent acute pancreatitis and substantial morbidity, requiring early identification and prompt management to prevent complications.
Population
An 11-year-old female with xanthogranulomatous pancreatitis and fasting triglyceride levels exceeding 4000 mg/dL
Design
Case report
Follow-up
12-month
Authors
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Supports insulin-MCT diet consideration in pediatric hypertriglyceridemic pancreatitis; hypothesis-generating and requires prospective trials.
Case Report (n=1)
Continuous intravenous insulin combined with a specialized low-LCT/high-MCT diet safely and effectively managed extreme hypertriglyceridemia and prevented recurrent pancreatitis in a pediatric patient.
Spoială et al. (2026) conducted a case report in Severe hypertriglyceridemia (n=1). Continuous intravenous aspart insulin and specialized diet was evaluated on Triglyceride reduction. Continuous intravenous aspart insulin and a specialized diet reduced triglyceride levels by 82% at 96 hours and prevented pancreatitis recurrence over 12 months in an 11-year-old girl.
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