Why the study?
Does spinal transection alter the circadian rhythm of leg peripheral resistance compared to able-bodied subjects?
Population
22 subjects (11 normal able-bodied humans and 11 patients with spinal transection due to spinal cord injury)
Comparison
Observation during 24 hours of bed confinement… vs Able-bodied subjects compared to patients with…
Design
Cross-sectional
Follow-up
24 hours
Authors
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Spinal cord injury may disrupt leg resistance circadian rhythms; leaves open causal role of neural traffic and need for prospective studies.
Does spinal transection alter the circadian rhythm of leg peripheral resistance compared to able-bodied subjects?
The circadian rhythm of leg peripheral resistance is modulated by spinal neural traffic, as evidenced by the loss of day-night differences in patients with spinal cord injury.
Edoardo Casiglia (1999) studied this question.
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