Edwin G. Williams, C. K. Himmelsbach, Abraham Wikler, Dorothy C. Ruble, Bolivar J. Lloyd, Jr., Studies on Marihuana and Pyrahexyl Compound, Public Health Reports (1896-1970), Vol. 61, No. 29 (Jul. 19, 1946), pp. 1059-1083
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Williams et al. (1946) studied this question.