Key result
Low haemoglobin levels (<8.0 g/dL) at presentation were significantly associated with increased in-hospital mortality (p=0.02) among patients with STEMI undergoing primary PCI.
Why the study?
The study aimed to evaluate the impact of low haemoglobin levels on in-hospital mortality among patients with STEMI undergoing primary PCI.
Does low haemoglobin increase in-hospital mortality in STEMI patients undergoing primary PCI?
Observational (n=250)
No
Does low haemoglobin increase in-hospital mortality in STEMI patients undergoing primary PCI?
p-value: p=0.02
Low haemoglobin levels (<8.0 g/dL) at presentation are independently associated with significantly increased in-hospital mortality among STEMI patients undergoing primary PCI.
Low Hb (<8 g/dL) at presentation flags higher in-hospital mortality after STEMI primary PCI; leaves open whether correction improves outcomes.
Objective: This study aimed to evaluate the impact of low haemoglobin levels on in-hospital mortality among patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) at NICVD (National Institute of Cardiology) Karachi. Methodology: A retrospective observational study was conducted from May 17, 2023 to November 17, 2023, including 250 STEMI patients. Data on demographics, haemoglobin levels, comorbidities, and procedural outcomes were analyzed. The association between low haemoglobin and in-hospital mortality was assessed using chi-square tests, t-tests, and logistic regression models, with statistical significance set at p<0.05. Results: The study included 150 males (60%) and 100 females (40%) with a mean age of 58.4 years. The majority (84%) were diagnosed with STEMI, and 98% underwent PCI. Haemoglobin levels ranged from 7.0 to 11.0 g/dL. In-hospital mortality was 8% (20/250), significantly higher in patients with haemoglobin <8.0 g/dL. Mortality was associated with diabetes (p=0.04) and hypertension (p=0.01). PCI success significantly correlated with survival (p=0.001). Low haemoglobin levels were independently associated with increased mortality (p=0.02). Conclusion: Low haemoglobin significantly increases in-hospital mortality in STEMI patients undergoing PCI. Early screening and management of anaemia are essential to improve outcomes. Further prospective studies are recommended to validate these findings and explore interventional strategies.
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Haq et al. (2025) conducted an observational in ST-elevation myocardial infarction (STEMI) (n=250). Low haemoglobin (<8.0 g/dL) vs. Haemoglobin >8.0 g/dL was evaluated on In-hospital mortality (p=0.02). Low haemoglobin levels (<8.0 g/dL) at presentation were significantly associated with increased in-hospital mortality (p=0.02) among patients with STEMI undergoing primary PCI.
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