May 1, 1999Clinical Science

Lisinopril improves arterial function in hyperlipidaemia

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Why the study?

Does lisinopril improve endothelial function in patients with hypercholesterolaemia?

Population

40 patients with hypercholesterolaemia

Comparison

Lisinopril 20 mg/day for 6 months vs Placebo for 6 months

Design

RCT, randomized, double-blind

Follow-up

6 months

Authors

ALAlison F. C. LeeNinewells Hospital JDJohn B.C. DICK CBClare E. BONNAR

Discussion

Member takes

Implication

Lisinopril improves endothelial function in hypercholesterolemia; confirms ACE inhibitor vascular benefits in RCT.

Structured PICO

Does lisinopril improve endothelial function in patients with hypercholesterolaemia?

Population

40 patients with hypercholesterolaemia

Intervention

Lisinopril 20 mg/day for 6 months

Comparator

Placebo for 6 months

Outcome

Endothelial function assessed by forearm blood flow responses to acetylcholine and sodium nitroprusside via venous occlusion plethysmography at 6 monthssurrogate

Lisinopril therapy for 6 months improves endothelial function and lowers blood pressure in patients with hypercholesterolemia.

Cite This Study

Lee et al. (1999) studied this question.

synapsesocial.com/papers/6a81ac1db35cb7638cee2755 https://doi.org/10.1042/cs19980386

View Full Paper

Ask AI

Bookmark

Lisinopril improves arterial function in hyperlipidaemia

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Lisinopril improves arterial function in hyperlipidaemia

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider