Key result
Patients with carotid atherosclerosis complicated by ischemic stroke had significantly higher average vascular stenosis degree detected by MRI compared to those without stroke (55.7% vs 26.3%, p<0.001).
Why the study?
The study was conducted to investigate the characterizations of CT and MRI in patients with carotid atherosclerosis.
Do CT and MRI differ in their ability to detect vulnerable plaque characteristics in patients with carotid atherosclerosis complicated by stroke?
Case-Control (n=264)
No
Do CT and MRI differ in their ability to detect vulnerable plaque characteristics in patients with carotid atherosclerosis complicated by stroke?
Both CT and MRI can identify vulnerable plaque characteristics in carotid atherosclerosis, with MRI being superior for detecting plaque hemorrhage and CT better for calcifications.
Answers are grounded in this paper and cite their sources.
MRI stenosis linked to stroke in carotid atherosclerosis; hypothesis-generating for risk stratification, needs prospective validation vs CT.
Background: To investigate the characterizations of CT (computed tomography) and MRI (magnetic resonance imaging) in patients with carotid atherosclerosis. Methods: A retrospective analysis was performed on the medical records of 264 patients with carotid atherosclerosis underwent CT and MRI in Linyi Central Hospital, Linyi, China from January 2010 to January 2016. Among them, 142 patients with ischemic stroke were in experimental group (test group), another 122 patients in control group. The lumen stenosis degree, plaque fibrous cap status, calcification information and vascular plaque hemorrhage in the carotid artery fork of patients detected by CT and MRI were collected. Results: The detection rate of the plaque calcification of patients detected by MRI was lower than that detected by CT in the experimental group (P<0.05). Patients in the experimental group had higher average vascular stenosis degree detected by CT and MRI than those in the control group (P<0.01). The average vascular stenosis degree of patients detected by MRI was higher than that detected by CT in the experimental group (P<0.05). Patients in the experimental group had higher unstable fibrous cap number detected by CT and MRI than those in the control group (P<0.01). Patients in the experimental group had significantly higher number of vascular plaque small focus hemorrhage than those in the control group (P<0.05). Conclusion: Patients with carotid atherosclerotic complicated with stroke have higher plaque calcification number, vascular stenosis degree and unstable fibrous cap number. Both CT and MRI can better predict the risk of stroke.
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Yang et al. (2020) conducted a case-control in Carotid atherosclerosis (n=264). Ischemic stroke vs. No stroke was evaluated on Average vascular stenosis degree detected by MRI (p=<0.001). Patients with carotid atherosclerosis complicated by ischemic stroke had significantly higher average vascular stenosis degree detected by MRI compared to those without stroke (55.7% vs 26.3%, p<0.001).
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