Why the study?
To investigate the association between adipose distribution and hepatic steatosis in American adults and evaluate whether it varies across different blood glucose states.
Is adipose distribution associated with hepatic steatosis across different blood glucose states in American adults?
Population
2986 American adult participants from NHANES 2017-2018
Comparison
Diabetes vs prediabetes vs normal glucose tolerance
Design
Cross-sectional analysis
Key result
Android to gynoid ratio (AGR) was the only adipose distribution parameter significantly correlated with hepatic steatosis in adults with diabetes (p=0.004).
Authors
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AGR may flag hepatic steatosis risk in diabetes; leaves open whether fat distribution patterns differ by glucose tolerance.
Cross-Sectional (n=2,986)
Is adipose distribution associated with hepatic steatosis across different blood glucose states in American adults?
p-value: p=0.004
Android to gynoid ratio is the only adipose distribution parameter that predicts hepatic steatosis in patients with diabetes, whereas multiple parameters are predictive in individuals with normal glucose tolerance.
Liu et al. (2023) conducted a cross-sectional in Hepatic steatosis (n=2,986). Adipose distribution parameters (e.g., android to gynoid ratio, VAT volume) was evaluated on Hepatic steatosis (p=0.004). Android to gynoid ratio (AGR) was the only adipose distribution parameter significantly correlated with hepatic steatosis in adults with diabetes (p=0.004).