Key result
Implementation of new cardiac anaesthesia protocols significantly reduced the mean length of hospitalization from 6.87 to 4.20 days (P=0.046) and decreased mechanical ventilation time.
Why the study?
Congenital cardiac disease remains a paediatric health-care issue in Africa, prompting an evaluation of cardiac anaesthesia protocol trends and surgical care efficiency before and after 2014.
Does the implementation of new cardiac anaesthesia protocols improve postoperative outcomes in children with congenital cardiac disease undergoing open-heart surgery?
Observational (n=118)
No
Does the implementation of new cardiac anaesthesia protocols improve postoperative outcomes in children with congenital cardiac disease undergoing open-heart surgery?
Absolute Event Rate: 4.2% vs 6.87%
p-value: p=0.046
Simplifying cardiac anaesthesia protocols and selecting simple cases significantly improved postoperative outcomes, including reduced mechanical ventilation time and hospital stay, in a paediatric open-heart surgery program in Africa.
May shorten paediatric cardiac surgery stays in low-resource settings; leaves open confirmation in randomized trials.
Background: Infant mortality due to congenital malformations has an incident rate of 8 cases per 1000 live births. Due to Africa's inadequate health-care systems, congenital cardiac disease (CCD) remains a paediatric health-care issue. CCD patients undergo an open-heart operation (OHO) at the Komfo Anokye Teaching Hospital (KATH) in Kumasi. Aim: This study aimed to compare trends of cardiac anaesthesia protocols before and after 2014 and to assess the efficiency and quality of surgical care provided to children with CCD following the implementation of new cardiac anaesthesia protocols in 2014. Materials and Methods: Groups A and B were represented by the years before and after 2014. This was a retrospective study involving 118 patients who underwent OHO under general anaesthesia from 2007 to 2016 after obtaining Institutional ethical approval. Results: In Groups A and B, the mean length of hospitalization in days and cardiac care unit stay in days were (6.87 ± 3.51 and 4.20 ± 3.66) ( P = 0.046) and (3.14 ± 2.37 and 1.96 ± 2.85) ( P = 0.382), respectively. In Group B, ultrafast track extubations increased from 7.25% to 39.71% ( P = 0.021), while patients mean mechanically ventilation time decreased by 82.34 ± 11.70–23.48 ± 7.94 h ( P = 0.018). In the first 48 h, the chest tube's postoperative drainage reduced by 133 ± 28.46–95 ± 20.38 ml ( P = 0.018) and haemorrhage leading to re-exploration decreased 11.77%–1.50% ( P = 0.019). After 2014, postoperative haemorrhage, the chest tube's drainage, and re-exploration were statistically significantly reduced by tranexamic acid. Conclusions: This ten-year program primarily focused on selecting simple cases and simplifying anaesthesia protocols after 2014. Given the success of our OHO program at KATH Kumasi, there is a need for a paradigm shift to sustain OHO programs in other parts of Africa.
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Singh et al. (2022) conducted an observational in Congenital cardiac disease (CCD) (n=118). New cardiac anaesthesia protocols (post-2014) vs. Old cardiac anaesthesia protocols (pre-2014) was evaluated on Mean length of hospitalization in days (p=0.046). Implementation of new cardiac anaesthesia protocols significantly reduced the mean length of hospitalization from 6.87 to 4.20 days (P=0.046) and decreased mechanical ventilation time.
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