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November 1, 1992Cardiovascular Research

Role of ATP dependent potassium channels in myocardial ischaemia

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GGG J GrossMedical College of Wisconsin JAJohn A. AuchampachMedical College of Wisconsin

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Implication

Dual KATP effects in ischaemia warrant caution against routine modulation; leaves open net benefit versus proarrhythmic risk.

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Cite This Study

Gross et al. (1992) studied this question.

synapsesocial.com/papers/6a81b00eac3bbfe76d60f437 https://doi.org/10.1093/cvr/26.11.1011

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Role of ATP sensitive potassium channel in extracellular potassium accumulation and cardiac arrhythmias during myocardial ischaemia1994 · 82 citations
2Functional Regulation of KATP Channels and Mutant Insight Into Clinical Therapeutic Strategies in Cardiovascular Diseases2022 · 8 citations
3Cardiac ATP-Sensitive Potassium Channels: A Potential Target for an Anti-Ischaemic Pharmacological Strategy2007 · 28 citations
4ATP-sensitive potassium channels: metabolic sensing and cardioprotection2007 · 125 citations
5Sarcolemmal KATP Channels in the Heart: Molecular Mechanisms Brought to Light, but Physiologic Consequences Still in the Dark2001 · 13 citations