Key result
Radical excision of left atrial myxoma-associated lymphoma achieves disease-free survival at 4 months.
Why the study?
Lymphomas arising from cardiac myxomas are particularly rare, with only a few cases reported in the literature.
Case Report (n=1)
No
This case demonstrates that cardiac myxomas with gelatinous, friable macroscopic features can conceal indolent EBV-positive fibrin-associated diffuse large B-cell lymphomas, reinforcing the need for radical surgical excision with wide safety margins.
Answers are grounded in this paper and cite their sources.
Rare myxoma-associated EBV+ lymphoma achieved short-term remission after excision; leaves open long-term surveillance needs and pathogenesis.
INTRODUCTION: Lymphomas arising from cardiac myxomas represent a particularly rare pathology, with only few cases reported in the literature.Case presentation: We report a complete excision of a malignant lymphoma arising from a cardiac myxoma in a 44-year-old female patient. The myxoma presented like a floating mass within the left atrium with a maximum diameter of 3.5 cm. The clinical post-operative period was uneventful and the patient was dismissed on the 6th post-operative day. CONCLUSION: This case reinforces the concept of radical excision of cardiac neoplasms.
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Pirola et al. (2022) conducted a case report in EBV-positive fibrin-associated large B-cell lymphoma arising within a left atrial cardiac myxoma (n=1). Radical surgical excision via left atriotomy was evaluated on Complete resection and disease-free survival at 4 months without adjuvant chemotherapy or radiotherapy. Radical surgical excision of a 3.5 cm left atrial myxoma harboring an EBV-positive fibrin-associated large B-cell lymphoma resulted in an uneventful discharge on day 6 and no disease at 4 months.
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