Key result
Incorporating ventricular wall motion with 3D colour Doppler data reduced blood flow reconstruction error and produced more plausible flow patterns compared to using Doppler data alone.
Incorporating ventricular wall motion from B-mode ultrasound improves the accuracy and plausibility of 4D intracardiac blood flow reconstruction from color Doppler data, especially when ventricular coverage is incomplete.
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Enhances 4D intracardiac flow reconstruction accuracy; leaves open prospective clinical validation.
We demonstrate a new method to recover 4D blood flow over the entire ventricle from partial blood velocity measurements using multiple 3D+t colour Doppler images and ventricular wall motion estimated using 3D+t BMode images. We apply our approach to realistic simulated data to ascertain the ability of the method to deal with incomplete data, as typically happens in clinical practice. Experiments using synthetic data show that the use of wall motion improves velocity reconstruction, shows more accurate flow patterns and improves mean accuracy particularly when coverage of the ventricle is poor. The method was applied to patient data from 6 congenital cases, producing results consistent with the simulations. The use of wall motion produced more plausible flow patterns and reduced the reconstruction error in all patients.
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Gómez et al. (2015) studied Congenital heart disease (n=6). 4D blood flow reconstruction incorporating ventricular wall motion and colour Doppler vs. Reconstruction using colour Doppler data only was evaluated on Reconstruction error in velocity magnitude (p=<0.001). Incorporating ventricular wall motion with 3D colour Doppler data reduced blood flow reconstruction error and produced more plausible flow patterns compared to using Doppler data alone.
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