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February 28, 2017EP EuropaceOpen Access

Very long-term outcome following transcatheter ablation of atrial fibrillation. Are results maintained after 10 years of follow up?

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Key result

Over a 10-year follow-up after transcatheter ablation for atrial fibrillation, 52% of patients remained arrhythmia-free, while 10% progressed to permanent AF.

Population

255 patients referred for atrial fibrillation ablation in a single high volume centre.

Design

Cohort

Follow-up

125 ± 7 months

Authors

FGFiorenzo GaïtaElectrophysiologyMSMarco ScaglioneElectrophysiologyABAlberto BattagliaElectrophysiology

Discussion

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Overview

May inform shared decision-making on AF ablation durability; extends observational data but leaves open need for randomized confirmation.

Study Design

Type

Cohort (n=255)

Multicenter

No

Structured PICO

P
Population
255 patients (77% male, 42.7% paroxysmal AF) referred for atrial fibrillation ablation, followed prospectively for 125 ± 7 months.
E
Exposure
Transcatheter ablation of atrial fibrillation
O
Outcome
Arrhythmia-free survival and progression to permanent AF at 125 ± 7 months follow-up, assessed by yearly clinical assessment and Holter monitoring

Transcatheter ablation for atrial fibrillation provides sustained arrhythmia-free survival in approximately half of patients over a 10-year period, with strict control of blood pressure, BMI, and fasting glucose protecting against recurrence.

Cite This Study

Gaïta et al. (2017) conducted a cohort in Atrial fibrillation (n=255). Transcatheter ablation was evaluated on Arrhythmia-free survival. Over a 10-year follow-up after transcatheter ablation for atrial fibrillation, 52% of patients remained arrhythmia-free, while 10% progressed to permanent AF.

synapsesocial.com/papers/6a81bb335fe02a08f3d82a82https://doi.org/10.1093/europace/eux008
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Catheter Ablation of Atrial Fibrillation in Patients With Left Ventricular Systolic Dysfunction2014 · 173 citations
  2. 2Long-Term Clinical Results of 2 Different Ablation Strategies in Patients With Paroxysmal and Persistent Atrial Fibrillation2008 · 212 citations
  3. 3Aggressive Risk Factor Reduction Study for Atrial Fibrillation and Implications for the Outcome of Ablation2014 · 957 citations
  4. 4Left atrial volume at MRI is the main determinant of outcome after pulmonary vein isolation plus linear lesion ablation for paroxysmal-persistent atrial fibrillation2010 · 33 citations
  5. 5Five-year efficacy of pulmonary vein antrum isolation as a primary ablation strategy for atrial fibrillation: a single-centre cohort study2016 · 45 citations