Key result
Women with a history of coronary heart disease were significantly less likely than men to be prescribed ≥3 recommended medications (44% vs 61%, p<0.001).
Why the study?
To determine whether sex differences exist in the management of patients with a history of coronary heart disease in primary care.
Are there sex differences in the management and secondary prevention of coronary heart disease in primary care?
Observational (n=130,926)
Yes
Are there sex differences in the management and secondary prevention of coronary heart disease in primary care?
Absolute Event Rate: 44% vs 61%
p-value: p=<0.001
Significant sex disparities persist in the secondary prevention of coronary heart disease in primary care, with women being underprescribed recommended medications and less frequently assessed for risk factors compared to men.
Sex disparities in CHD secondary prevention persist in primary care; this observational finding leaves open causal factors and intervention effects.
OBJECTIVES: To determine whether sex differences exist in the management of patients with a history of coronary heart disease (CHD) in primary care. METHODS: General practice records of patients aged ≥18 years with a history of CHD in a large general practice dataset in Australia, MedicineInsight, were analysed. Sex-specific, age-standardised proportions of patients prescribed with recommended medications; assessed for cardiovascular risk factors; and achieved treatment targets according to the General Practice Management Plan were reported. RESULTS: Records of 130 926 patients (47% women) from 438 sites were available from 2014 to 2018. Women were less likely to be prescribed with recommended medications (prescribed ≥3 medications: women 44%, men 61%; p<0.001). Younger patients, especially women aged <45 years, were substantially underprescribed (aged <45 years prescribed ≥3 medications: women 2%, men 8%; p<0.001). Lower proportions of women were assessed for cardiovascular risk factors (blood test for lipids: women 70%-76%, men 77%-81%; p<0.001). Body size was not commonly assessed (body mass index: women 59%, men 62%; p<0.001; waist: women 23%, men 25%; p<0.001). Higher proportions of women than men achieved targets for most risk factors (achieved ≥4 targets in patients assessed for all risk factors: women 82%, men 76%). CONCLUSION: Gaps in preventative management including prescription of indicated medications and risk factor monitoring have been reported from the late 1990s and this large-scale general practice data analysis indicate they still persist. Moreover, the gap is larger in women compared to men. We need new ways to address these gaps and the sex inequity.
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Lee et al. (2019) conducted an observational in Coronary heart disease (n=130,926). Female sex vs. Male sex was evaluated on Prescription of ≥3 recommended medications (p=<0.001). Women with a history of coronary heart disease were significantly less likely than men to be prescribed ≥3 recommended medications (44% vs 61%, p<0.001).
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