Why the study?
What are the risk factors for amiodarone-induced pulmonary toxicity in patients receiving amiodarone?
Population
n=244 cases of amiodarone-induced pulmonary toxicity, comprising 237 cases from Australian and US drug…
Design
Cohort
Authors
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May identify highest-risk patients for amiodarone pulmonary toxicity; leaves open whether targeted monitoring improves outcomes.
What are the risk factors for amiodarone-induced pulmonary toxicity in patients receiving amiodarone?
Patient age (>60 years) and duration of amiodarone therapy (6-12 months) are the most significant risk factors for amiodarone-induced pulmonary toxicity, suggesting targeted monitoring is warranted for these patients.
Ernawati et al. (2008) studied this question.
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