Key result
Serum C-type natriuretic peptide levels were similar between healthy young men and women, with no significant correlation to reproductive hormones or semen parameters.
Why the study?
The study was conducted to compare serum C-type natriuretic peptide levels between healthy males and females and evaluate their relationship with ovarian function markers and sperm parameters.
Cross-Sectional (n=40)
No
Serum CNP levels do not significantly differ between healthy young men and women and do not correlate with baseline reproductive hormones or semen parameters.
Answers are grounded in this paper and cite their sources.
Serum CNP unlikely to inform fertility evaluation in healthy adults; leaves open prospective studies in reproductive disorders.
OBJECTIVE Firstly we aimed to compare serum C-type natriuretic peptide (CNP) levels in healthy male and female participants of similar age group and secondly to reveal the relationship between serum CNP values and ovarian function markers in women and sperm parameters in men. MATERIAL and METHODS In this prospective study, a total of 40 patients, who were admitted to the Department of Obstetrics and Gynecology at Near East University Hospital were included. Of these, 20 were female and 20 were male participants. Serum CNP levels of the patients were analyzed for all participants. Day 3 serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) for female participants and semen samples after 3-5 days of sexual abstinence for male participants were evaluated. RESULTS Serum CNP levels were similar in both genders. There was only a moderate, but statistically insignificant negative correlation between serum CNP and FSH in female group. In the correlation analysis performed in the male group, no significant correlation was observed between serum CNP level and any semen analysis parameter. CONCLUSION We showed that serum CNP levels were similar between healthy women and men. There was no relationship between levels of serum CNP and reproductive hormones in the early follicular phase of menstruation in women, and semen parameters in men.
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Özay et al. (2022) conducted a cross-sectional in Healthy (n=40). Male sex vs. Female sex was evaluated on Serum C-type natriuretic peptide (CNP) levels (pg/mL) (p=0.341). Serum C-type natriuretic peptide levels were similar between healthy young men and women, with no significant correlation to reproductive hormones or semen parameters.
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