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The fibrinolytic activity of human leukocytes was studied by the fibrin plate method and by the histochemical fibrin slide method, using plasminogen-rich and plasminogen-free fibrin substrates. Lysis is caused by a protease. Plasminogen activator is absent. The slide method showed the effect of leukocytes to be weak in comparison to that produced by the plasminogen activator in capillary endothelial cells invading fibrin deposits in the body.
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Astrup et al. (1967) studied this question.
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