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February 1, 2016Therapeutics and Clinical Risk ManagementOpen Access

Optimal medical therapy for secondary prevention after an acute coronary syndrome: 18-month follow-up results at a tertiary teaching hospital in South Korea

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Why the study?

Does the persistence of guideline-recommended secondary prevention medications decline over 18 months in patients discharged after acute coronary syndrome?

Population

494 patients discharged after acute coronary syndrome treatment from a tertiary hospital in South Korea…

Design

Cohort

Follow-up

18 months

Authors

ECEun Joo ChoiChosun University HBHee Ja ByeonChosun University Hospital YYYoung-Mo YangChosun University

Discussion

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Implication

Declining post-ACS persistence of guideline-directed therapy signals need for closer monitoring; leaves open optimal real-world adherence strategies.

Structured PICO

Does the persistence of guideline-recommended secondary prevention medications decline over 18 months in patients discharged after acute coronary syndrome?

P

Population

494 patients discharged after acute coronary syndrome (ACS) treatment from a tertiary hospital in South Korea between September 2009 and August 2013.

I

Intervention

Guideline-recommended secondary prevention drug therapy (aspirin, clopidogrel, beta-blocker, angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker, and statin)

O

Outcome

Prescription patterns and persistence of secondary prevention drugs at discharge and at 3, 6, 12, and 18 months after discharge

While the majority of ACS patients receive guideline-recommended secondary prevention medications at discharge, adherence significantly declines over 18 months, highlighting the need for careful monitoring.

Cite This Study

Choi et al. (2016) studied this question.

synapsesocial.com/papers/6a81e0189e5e8e4efb4d7654 https://doi.org/10.2147/tcrm.s99869

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Secondary prevention therapies in acute coronary syndrome and relation to outcomes: observational study2019 · 39 citations
2Evaluation of Medication Compliance for Secondary Prevention of Acute Coronary Syndrome2017 · 7 citations
3Use of Secondary Prevention Drug Therapy in Patients With Acute Coronary Syndrome After Hospital Discharge2008 · 122 citations
4Evaluation of discharge prescriptions for secondary prevention in patients with acute coronary syndromes in Iraq2019 · 8 citations
5Adherence to guidelines for the prescription of secondary prevention medication at hospital discharge after acute coronary syndrome: a multicentre study2015 · 29 citations