Why the study?
Preexcitation syndrome impairs normal cardiac conduction, but radiofrequency ablation is rare in women with preexcitation syndrome during pregnancy.
Does radiofrequency catheter ablation safely resolve paroxysmal supraventricular tachycardia in a pregnant woman with preexcitation syndrome?
Does radiofrequency catheter ablation safely resolve paroxysmal supraventricular tachycardia in a pregnant woman with preexcitation syndrome?
Radiofrequency catheter ablation can be safely and effectively performed in pregnant women with preexcitation syndrome and refractory supraventricular tachycardia to improve maternal-fetal outcomes.
May support ablation for refractory cases in pregnancy; hypothesis-generating and should not yet change practice.
RATIONALE: Preexcitation syndrome is an uncommon congenital cardiac disorder that impairs the normal cardiac conduction system. Radiofrequency ablation is one of the most effective treatments for this condition. Nevertheless, radiofrequency ablation is rare in women with preexcitation syndrome during pregnancy. PATIENT CONCERNS: A 33-year-old woman with monochorionic diamniotic twin pregnancy complicated by sinus arrhythmia with ventricular preexcitation at 14 weeks and 5 days of gestation, with paroxysmal palpitations and shortness of breath at 16 weeks with paroxysmal supraventricular tachycardia with preexcitation syndrome and a heart rate ranging from 180 to 225 beats per minute. DIAGNOSES: The pregnant occurred sudden palpitations and shortness of breath in the shower. Electrocardiography revealed paroxysmal supraventricular tachycardia, and electrophysiological study revealed preexcitation syndrome (dominant accessory route of the left free wall) with atrioventricular reentrant tachycardia. INTERVENTIONS: Radiofrequency catheter ablation was performed at 20 weeks. OUTCOMES: Symptoms of preexcitation syndrome resolved after the radiofrequency catheter ablation, and 2 healthy infants were delivered at 36 weeks and 2 days of gestation by cesarean section. LESSONS: Preexcitation syndrome may result in life-threatening arrhythmias such as supraventricular tachycardia during pregnancy and delivery. It might be efficiently controlled through optimal treatment by a multidisciplinary team, which would effectively minimize arrhythmia risk events during pregnancy and improve maternal-fetal outcomes. Based on the patient's individual situation, radiofrequency ablation may be a procedure in pregnant women with preexcitation syndrome.
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Liao et al. (2024) studied this question.
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