Key result
Among women undergoing catheter ablation, pregnant women had a significantly higher prevalence of accessory pathway-related arrhythmias or atrial tachycardia (62%) compared to non-pregnant controls (32%).
Why the study?
Does catheter ablation without fluoroscopy using electroanatomical mapping provide safe and feasible treatment for cardiac arrhythmias in pregnant women compared to non-pregnant women?
Case-Control (n=122)
Does catheter ablation without fluoroscopy using electroanatomical mapping provide safe and feasible treatment for cardiac arrhythmias in pregnant women compared to non-pregnant women?
Absolute Event Rate: 62% vs 32%
p-value: p=0.042
Catheter ablation of arrhythmias during pregnancy without fluoroscopy using electroanatomical mapping is feasible and safe, with accessory pathways and atrial tachycardia being the most common indications.
Zero-fluoroscopy ablation appears feasible and safe in select pregnant patients; leaves open need for prospective trials before wider adoption.
BACKGROUND: Cardiac arrhythmias are common in pregnant women. In most cases, they do not require treatment other than rest, electrolyte supplementation and avoidance of strong coffee and tea. Persistent arrhythmia or the ventricular rate running at a high frequency may cause hemodynamic deterioration in the fetus or in both the fetus and the mother. OBJECTIVES: The aim of this study was to assess the prevalence and characteristics of arrhythmias in pregnant women who qualified for ablation as well as the feasibility and specific features of these interventions. MATERIAL AND METHODS: The study group consisted of 11 pregnant women (16-32 Hbd) aged 31 + 6. The control group consisted of 111 women aged 15-50 years (34 + 10), scheduled for ablation in 2012. The medical records of the selected study and control groups were analyzed and the following data was retrieved: age, the reason the ablation procedure was performed, the ablation duration, the number of radiofrequency applications, the total duration of radiofrequency applications, gravity, and comorbidities. RESULTS: In the study group, accessory pathway related arrhythmias or atrial tachycardia (AT) accounted for 62% of cases, whereas in the control group for 32% (p = 0.042). All the procedures in the study group were performed with an electroanatomical system without fluoroscopy. All of the patients, but one, had no recurrence of arrhythmia. There were no complications and no overt effects were noted in the fetus. CONCLUSIONS: Ablation of arrhythmias during pregnancy is rare. An experienced surgeon using electroanatomical system is usually able to ablate arrhythmic substrate without the use of X-ray fluoroscopy. The most prevalent causes of arrhythmias in pregnant women requiring ablation are accessory pathway and AT focus.
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Koźluk et al. (2017) conducted a case-control in Cardiac arrhythmias (n=122). Pregnancy vs. Non-pregnant women was evaluated on Prevalence of accessory pathway related arrhythmias or atrial tachycardia (AT) (p=0.042). Among women undergoing catheter ablation, pregnant women had a significantly higher prevalence of accessory pathway-related arrhythmias or atrial tachycardia (62%) compared to non-pregnant controls (32%).
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