Why the study?
It was unknown whether skin or core temperatures modulate vascular adaptations to acute heat exposure, independent of elevations in vascular shear stress.
Do skin and core temperatures modulate flow-mediated dilation of the brachial artery following passive heating?
Do skin and core temperatures modulate flow-mediated dilation of the brachial artery following passive heating?
Skin and core temperatures independently modify acute vascular responses to passive heating, beyond the effects of shear stress alone.
No change to clinical heating protocols warranted; extends evidence that temperature independently shapes vascular reactivity beyond shear.
The primary determinant of vascular adaptations to lifestyle interventions, such as exercise and heat therapy, is repeated elevations in vascular shear stress. Whether skin or core temperatures also modulate the vascular adaptation to acute heat exposure is unknown, likely due to difficulty in dissociating the thermal and hemodynamic responses to heat. We found that skin and core temperatures modify the acute vascular responses to passive heating irrespective of the magnitude of increase in shear stress.
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Coombs et al. (2020) studied this question.
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