Why the study?
Does acute whole body passive heat stress and arterial shear rate modification affect radial artery function in young men?
Does acute whole body passive heat stress and arterial shear rate modification affect radial artery function in young men?
Shear rate changes drive conduit artery responses to acute whole body heat stress, with attenuated flow-mediated vasodilation as the vasodilatory limit is reached.
FMD requires cautious interpretation during acute heating; leaves open clinical relevance beyond young men.
We observed that acute whole body heating elevates radial artery shear rate, diameter, and blood flow. This results in a diminished flow-meditated dilatation (FMD) but does not change low-flow-mediated constriction (L-FMC). Preventing shear rate changes during whole body heating reduces radial artery vasodilation and reverses FMD reductions but has no effect on L-FMC. These findings indicate that shear rate changes underpin conduit artery responses to acute whole body heat stress, but further endothelium-dependent flow-mediated vasodilation is attenuated as the vasodilatory range limit is approached.
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Alali et al. (2020) studied this question.
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