Intravenous insulin therapy successfully and rapidly reduced severe hypertriglyceridemia in a patient presenting with acute pancreatitis.
May support insulin infusion for rapid triglyceride reduction in pancreatitis; hypothesis-generating case leaves efficacy unproven.
Hypertriglyceridemia (HTG) is a known cause of pancreatitis. We described a case of severe hypertriglyceridemia (likely familial) causing the first episode of pancreatitis in this patient. A 21-year-old female known for hypertriglyceridemia and DM type 2 came to the emergency room with severe epigastric pain along with nausea and vomiting. Physical exam revealed epigastric tenderness, diminished bowel sounds, and signs of dehydration. Initial blood work was mostly unremarkable mildly elevated lipase 83.
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Pankaj Agrawal (2022) studied this question.
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