July 1, 1999Journal of Pediatric Gastroenterology and Nutrition

Neonatal Pancreatitis Associated with Familial Lipoprotein Lipase Deficiency

View Full Paper

Ask AI

Bookmark

Population

1 neonate presenting with fever, irritability, bilious emesis, and abdominal distension, subsequently…

Design

Case_report

Follow-up

3 months

Authors

CSConstantinos G. Siafakas MBMarilyn R. BrownHealth & Life (Taiwan)TMTracie L. MillerUniversity of Missouri–Kansas City

Discussion

Member takes

Implication

Supports fat restriction for neonatal LPL deficiency; leaves open need for confirmatory studies.

Structured PICO

Population

1 neonate (3-week-old full-term boy) presenting with fever, irritability, bilious emesis, and abdominal distension, subsequently diagnosed with acute pancreatitis secondary to massive hypertriglyceridemia caused by familial lipoprotein lipase deficiency.

Intervention

Exploratory laparotomy followed by total parenteral nutrition without lipid infusion for 4 days, then oral feedings with a formula high in medium-chain triglycerides (Portagen).

Outcome

Resolution of symptoms and reduction of serum triglyceride and cholesterol levels.

Familial lipoprotein lipase deficiency can present as early as the neonatal period with massive hypertriglyceridemia and acute pancreatitis, which can be effectively managed with dietary fat restriction.

Cite This Study

Siafakas et al. (1999) studied this question.

synapsesocial.com/papers/6a81e6a2a2b9faa7beb6c8fb https://doi.org/10.1097/00005176-199907000-00023

View Full Paper

Ask AI

Bookmark

Neonatal Pancreatitis Associated with Familial Lipoprotein Lipase Deficiency

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Neonatal Pancreatitis Associated with Familial Lipoprotein Lipase Deficiency

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider