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Article AbstractLetter to the Editor Sir: The new antidepressant mirtazapine (Remeron) has a unique mode of action, combining an increase of noradrenergic and 5-HT1A-mediated serotonergic neurotransmission with a specific blockade of 5-HT2 and 5-HT3-receptor subtypes. So far, a single case of overdose with mirtazapine has been reported since its introduction in The Netherlands in September 1994; I now report the second case.
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Anthony W. Gerritsen (1997) studied this question.
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