Why the study?
Neuroleptic malignant syndrome had not been previously associated with Takotsubo cardiomyopathy.
This case highlights a rare association between neuroleptic malignant syndrome and Takotsubo cardiomyopathy, emphasizing the need for clinical awareness.
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Alerts clinicians to possible Takotsubo cardiomyopathy in neuroleptic malignant syndrome; single case leaves association hypothesis-generating.
Neuroleptic malignant syndrome is a potentially fatal neurological condition secondary to antipsychotic medication. It is characterized by distinctive clinical findings and autonomic disturbances. NMS has not been associated with Takotsubo cardiomyopathy (TCM). TCM is an abnormal response to physiological stressors resulting from the autonomic abnormalities which at times can mimic myocardial infarction (MI). We present a unique case of a 54-year-old female with bipolar disease presenting with lithium and haloperidol-induced NMS complicated by TCM. The purpose of this case is to make clinicians aware of this rare association.
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Ullah et al. (2020) studied this question.
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