Inhalational induction with sevoflurane and careful perioperative management can be safely used in severely anaemic, agitated schizophrenic patients with a history of NMS requiring emergency surgery.
Administering anaesthesia to a patient with chronic schizophrenia is a challenge due to the increased risk of various perioperative complications. Neuroleptic agents are highly effective drugs used for the treatment of psychiatric disorders, but are rarely associated with neuroleptic malignant syndrome (NMS). Here, we describe the successful anaesthetic management of a patient of chronic schizophrenia with past history of NMS who presented in emergency with active bleeding per rectum and haemoglobin of 3 gm%.
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Rajwade et al. (2011) studied this question.
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