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April 22, 2015BMJOpen Access

Prognostic capabilities of coronary computed tomographic angiography before non-cardiac surgery: prospective cohort study

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Why the study?

Does preoperative coronary computed tomographic angiography improve prediction of cardiovascular death and non-fatal myocardial infarction in patients undergoing non-cardiac surgery?

Population

955 patients with, or at risk of, atherosclerotic disease who underwent non-cardiac surgery, multinational.

Comparison

Preoperative coronary computed tomographic… vs Revised cardiac risk index alone

Design

Cohort, Clinicians were blinded to the results unless left main disease was…

Follow-up

30 days

Authors

TSTej ShethInterventional CardiologyMatthew T.V. ChanMatthew T.V. ChanPrince of Wales HospitalCBCraig ButlerUniversity of Alberta

Discussion

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Implication

CCTA may aid perioperative risk stratification in non-cardiac surgery; leaves open routine adoption given net overestimation and observational design.

Structured PICO

Does preoperative coronary computed tomographic angiography improve prediction of cardiovascular death and non-fatal myocardial infarction in patients undergoing non-cardiac surgery?

P
Population
955 patients with, or at risk of, atherosclerotic disease who underwent non-cardiac surgery, multinational (12 centers in 8 countries).
I
Intervention
Preoperative coronary computed tomographic angiography (CCTA)
C
Comparator
Revised cardiac risk index alone
O
Outcome
Composite of cardiovascular death and non-fatal myocardial infarction within 30 days after surgerycomposite

Preoperative CCTA improves perioperative risk prediction for non-cardiac surgery but leads to a high rate of inappropriate risk overestimation in patients who do not experience events.

Cite This Study

Sheth et al. (2015) studied this question.

synapsesocial.com/papers/6a81f42a916951def24cecefhttps://doi.org/10.1136/bmj.h1907
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Combining Clinical and Thallium Data Optimizes Preoperative Assessment of Cardiac Risk before Major Vascular Surgery1989 · 731 citations
  2. 2Effect of Screening for Coronary Artery Disease Using CT Angiography on Mortality and Cardiac Events in High-Risk Patients With Diabetes2014 · 383 citations
  3. 3Combining Clinical and Thallium Data Optimizes Preoperative Assessment of Cardiac Risk Before Major Vascular Surgery1990 · 22 citations
  4. 4Association Between Postoperative Troponin Levels and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery2012 · 1,128 citations
  5. 5Risk Stratification Using Computed Tomography Coronary Angiography in Patients Undergoing Intermediate-Risk Noncardiac Surgery2013 · 61 citations