Why the study?
Early diagnosis of left ventricular thrombus can prevent end-organ ischemic events, but is complicated by the lack of easily accessible diagnostic modalities like cardiac MRI in the emergency department.
Bedside POCUS in the emergency department can rapidly identify left ventricular thrombus in high-risk patients, expediting confirmatory imaging and the initiation of anticoagulation.
May support POCUS for rapid ED LV thrombus detection; hypothesis-generating, requires prospective validation before practice change.
Left ventricular thrombus is a possible complication of heart failure, acute ischemic myocardial infarction, or progressive nonischemic cardiomyopathy. Early diagnosis of left ventricular thrombus can prevent end-organ ischemic events; however, it is complicated by the lack of easily accessible diagnostic modalities such as cardiac magnetic resonance imaging in the emergency department (ED). Here we present a case series of three patients who had point-of-care ultrasound (POCUS) evidence of left ventricular thrombus in the ED, which provided the emergency physician with valuable information that could be communicated to consulting and admitting teams. The case series illustrates the various common pathologic presentations associated with left ventricular thrombus: non-ischemic cardiomyopathy, ischemic cardiomyopathy, and sequelae of end-organ dysfunction such as cerebrovascular occlusions. Early recognition of left ventricular thrombus through POCUS can expedite subsequent management, and further studies are needed to demonstrate its effect on patient morbidity and mortality.
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Mitina et al. (2025) studied this question.
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