Two years have passed since the initial description of the Middle East respiratory syndrome coronavirus (MERS-CoV), yet the epidemic is far from being controlled. The high case fatality rate, the recent steep increase in reported cases, and the potential to cause a global pandemic during the upcoming Hajj season are serious concerns. Although a wealth of information about the pathophysiology, proposed animal reservoir, and intermediate host has been revealed, many questions remain unanswered. We herein review MERS-CoV, covering its proposed origins, route of transmission, treatment options, and future perspectives.
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Sharif-Yakan et al. (2014) studied this question.
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