Why the study?
Infection by rhinovirus and enterovirus in children can cause severe lower respiratory tract infection, but the clinical impact of specific species alone or in codetection with other viruses needed evaluation.
Does the presence of viral codetections affect clinical severity in young children with severe RV/EV lower respiratory tract infection?
Population
71 patients aged less than 5 years admitted to the PICU with RV or EV LRTI
Comparison
RV/EV species alone vs in codetection with other viruses
Design
Prospective cohort study
Authors
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Single RV/EV detection may signal IMV risk comparable to RSV in children; leaves open whether multiple codetections reduce severity.
Does the presence of viral codetections affect clinical severity in young children with severe RV/EV lower respiratory tract infection?
In young children with severe LRTI, single RV/EV infection can cause severe disease requiring mechanical ventilation, while multiple viral codetections may be associated with reduced clinical severity.
Penela‐Sánchez et al. (2021) studied this question.
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