Answers are grounded in this paper and cite their sources.
The biosynthesis and macromolecular organization of proteoglycans was studied in explants of adult human articular cartilage. In a series of pulse-chase experiments, labelling with (35S)sulphate, it was shown that the proteoglycan monomer is synthesized as a precursor that has a low affinity for hyaluronic acid. These findings suggest a possible mechanism by which the rate of incorporation of proteoglycans into the extracellular matrix may be controlled.
No takes yet. Share an insight, caveat, or question.
Bayliss et al. (1984) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: