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March 3, 2020Otolaryngology

The average heart rate during PSG was the strongest independent predictor of each HRV parameter (P < .001), and eAT-induced changes in HRV were not causally attributable to changes in AHI or ODI.

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Why the study?

Heart rate variability may represent the physiologic burden of OSA, prompting evaluation of whether treatment-related effects on HRV in children are causally attributable to improvement in OSA severity.

Does early adenotonsillectomy improve heart rate variability in children with obstructive sleep apnea?

Population

404 children aged 5 to 10 years with OSA

Comparison

Early adenotonsillectomy vs watchful waiting

Design

Secondary analysis of trial outcomes

Authors

AIAmal IsaiahDBDylan BertoniKPKevin D. Pereira

Discussion

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Overview

Changes in HRV after early adenotonsillectomy track average heart rate rather than apnea severity in children with OSA; leaves open whether treatment improves autonomic function.

Structured PICO

Does early adenotonsillectomy improve heart rate variability in children with obstructive sleep apnea?

P
Population
404 children aged 5 to 10 years with obstructive sleep apnea (OSA), median age 6, 48% male, 36% African American.
I
Intervention
Early adenotonsillectomy (eAT)
C
Comparator
Watchful waiting (WW)
O
Outcome
Changes in time- and frequency-domain heart rate variability (HRV) parameters and their causal attribution to changes in OSA severity (AHI and ODI)surrogate

In children with obstructive sleep apnea, changes in heart rate variability following early adenotonsillectomy are strongly modulated by average heart rate rather than specific improvements in apnea severity.

Cite This Study

Isaiah et al. (2020) studied this question.

synapsesocial.com/papers/6a8216e726d6a9977199d0bfhttps://doi.org/10.1177/0194599820907882
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