Relation between body mass index, waist circumference, and cardiovascular outcomes in 19,579 diabetic patients with established vascular disease: the REACH Registry
Why the study?
Does higher BMI or waist circumference associate with better cardiovascular outcomes in diabetic patients with established vascular disease?
Population
19,579 type 2 diabetic patients with established atherosclerotic arterial disease from the REACH Registry
Comparison
Higher Body Mass Index and waist circumference vs Lower BMI and waist circumference categories
Design
Cohort
Follow-up
2 years
Authors
Discussion
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Member takes
Overview
Should not yet alter risk stratification by BMI in diabetic vascular disease; leaves open whether waist circumference better captures adiposity-related risk.
Structured PICO
Does higher BMI or waist circumference associate with better cardiovascular outcomes in diabetic patients with established vascular disease?
P
Population
19,579 type 2 diabetic patients with established atherosclerotic arterial disease from the REACH Registry (international, prospective cohort)
I
Intervention
Higher Body Mass Index (BMI) and waist circumference
C
Comparator
Lower BMI and waist circumference categories
O
Outcome
All-cause death, cardiovascular death, MI, stroke, cardiovascular death/MI/stroke, and cardiovascular death/MI/stroke/rehospitalization at 2-year follow-uphard clinical
An obesity paradox exists when measured by BMI, but not waist circumference, in diabetic patients with established vascular disease, where higher BMI is associated with lower mortality and cardiovascular events.
Cite This Study
Dallongeville et al. (2011) studied this question.