Why the study?
Does perioperative beta-blocker prophylaxis reduce myocardial infarction or increase risks in patients undergoing noncardiac surgery?
Does perioperative beta-blocker prophylaxis reduce myocardial infarction or increase risks in patients undergoing noncardiac surgery?
Routine initiation of perioperative beta-blockers in naive patients undergoing noncardiac surgery is not recommended due to increased risks of severe stroke, hypotension, and bradycardia despite a reduction in myocardial infarction.
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Reinforces caution against routine perioperative beta-blocker initiation in naive noncardiac surgery patients; leaves open optimal selection for targeted trials.
White et al. (2010) studied this question.
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