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August 7, 2023Open Access

Loss of HSC stemness identity is associated with exhaustion and hyporesponsiveness in GATA2 deficiency syndrome

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Authors

LLLaëtitia LargeaudUniversité Toulouse III - Paul SabatierVFVincent FregonaMax Delbrück CenterLJLaura JamrogCentre National de la Recherche Scientifique

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Cite This Study

Largeaud et al. (2023) studied this question.

synapsesocial.com/papers/6a8222487db08d7cfd3f0f49https://doi.org/10.1101/2023.08.07.551811
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Also Consider

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  1. 1The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency2011 · 308 citations
  2. 2Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes2017 · 56 citations
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  4. 4GATA2 Germline Mutations Impair GATA2 Transcription, Causing Haploinsufficiency: Functional Analysis of the p.Arg396Gln Mutation2015 · 32 citations
  5. 5GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity2013 · 726 citations