Sc takes action: The highly enantioselective hydroxyamination reaction of N-unprotected 2-oxindoles with nitrosoarenes has been realized using the Sc(OTf)3/L1 complex. The catalyst system exhibited remarkably broad substrate scope and high efficiency. This transformation is the first example of a chiral ScIII/enolate activating a nitrosoarene, and can be conducted on a gram scale without loss in the ee values.
No takes yet. Share an insight, caveat, or question.
Shen et al. (2011) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: