Targeting the nuclear receptors: The ligand-binding domain of the glucocorticoid receptor (ribbon) bound with the ligand, dexamethasone (space-filling) is just one of the many pictures that are becoming clearer in the field of nuclear receptor (NR) research. Recent developments in drug discovery show great promise for the treatment of many NR-related diseases.
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Moore et al. (2006) studied this question.
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