Constrictive pericarditis should be considered in unexplained ascites even if liver histology lacks characteristic diffuse hepatic congestion.
Atypical liver histology should not exclude constrictive pericarditis in unexplained ascites; leaves open the need for prospective validation before changing diagnostic algorithms.
Cardiac ascites is a rare condition. Diagnosis is aided by liver histology, which characteristically shows diffuse hepatic congestion affecting the centrilobular region. In our case of refractory ascites due to constrictive pericarditis, diagnosis was delayed because centribular hepatic congestion was absent histologically. Contrary to numerous published reports, diffuse hepatic congestion is not uniformly present in cardiac ascites. Constrictive pericarditis is curable and should be considered in all cases of unexplained ascites, regardless of atypical hepatic histology.
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Bertram Fleshler (1992) studied this question.
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