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January 1, 1997European Heart JournalOpen Access

Risk stratification after myocardial infarction: A reappraisal in the era of thrombolysis

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Why the study?

What are the independent predictors of mortality in acute myocardial infarction patients in the thrombolytic era?

Population

471 acute myocardial infarction patients, 45% of whom were given thrombolytic therapy

Design

Cohort

Follow-up

mean 31.4 months

Authors

PTP TouboulCentre Hospitalier Universitaire de NiceXAXavier André‐FouëtUniversité Claude Bernard Lyon 1ALAlain LeizoroviczVascular Medicine

Discussion

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Implication

May refine post-MI risk stratification; leaves open whether targeted interventions improve outcomes.

Structured PICO

What are the independent predictors of mortality in acute myocardial infarction patients in the thrombolytic era?

P
Population
471 acute myocardial infarction patients, 45% of whom were given thrombolytic therapy
I
Intervention
Risk stratification tests including exercise test, radionuclide ventriculography, Holter monitoring, signal-averaged electrocardiography, and programmed electrical stimulation
O
Outcome
Mortality at 1 year and long-term (mean follow-up 31.4 months)hard clinical

Decreased heart rate variability, late potentials, and low ejection fraction (<30%) remain independent predictors of mortality after myocardial infarction in the thrombolytic era.

Cite This Study

Touboul et al. (1997) studied this question.

synapsesocial.com/papers/6a822bd6a8461dff0846c1cdhttps://doi.org/10.1093/oxfordjournals.eurheartj.a015125
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Long-term prognostic importance of patency of the infarct-related coronary artery after thrombolytic therapy for acute myocardial infarction.1994 · 229 citations
  2. 2Programmed ventricular stimulation in survivors of an acute myocardial infarction.1985 · 145 citations
  3. 3Late potentials detected after myocardial infarction: natural history and prognostic significance.1986 · 279 citations
  4. 4What is the best predictor of spontaneous ventricular tachycardia and sudden death after myocardial infarction?1991 · 172 citations
  5. 5Prognostic Value of Exercise Testing Soon after Myocardial Infarction1979 · 721 citations