An evaluation of standard and experimental topical repellents was made against the neotropical sand fly Lutzomyia longipalpis, using dose-response techniques. Deet, Indalone®, and Citronyl® were the most effective of the standard repellents tested on humans. Four experimental compounds, Rohm & Haas 398, 3-[N-(n-butyl)-N-acetyl]aminopropionic acid-ethyl ester, N-(n-hexyl)-2-oxazolidine, and methyl N,N′-di-(n-hexyl)-ethylenediamine monocarbamate showed significantly greater repellency than deet (P < 0.05) when tested on white rabbits. Comparative sensitivity of this sand fly species to repellents appears to be greater than that of certain mosquito, flea, tick, and reduviid bug species.
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Buescher et al. (1982) studied this question.