Why the study?
To examine in-hospital stroke onset metrics, outcomes, quality of care, and mortality compared with out-of-hospital stroke in a community-based primary stroke center.
Does in-hospital stroke onset result in worse time-sensitive stroke process metrics and outcomes compared to out-of-hospital stroke onset?
Does in-hospital stroke onset result in worse time-sensitive stroke process metrics and outcomes compared to out-of-hospital stroke onset?
In-hospital stroke onset is associated with significant delays in time-sensitive process metrics and higher mortality compared to out-of-hospital stroke onset.
May warrant targeted in-hospital stroke protocols; hypothesis-generating for trials testing whether faster response reduces mortality.
Objective To examine in-hospital stroke onset metrics and outcomes, quality of care, and mortality compared with out-of-hospital stroke in a single community-based primary stroke center. Patients and Methods Medical records of in-hospital stroke onset were compared with out-of-hospital stroke onset alert data between January 1, 2013 and December 31, 2019. Time-sensitive stroke process metric data were collected for each incident stroke alert. The primary focus of interest was the time-sensitive stroke quality metrics. Secondary focus pertained to thrombolysis treatment or complications, and mortality. Descriptive and univariable statistical analyses were applied. Kruskal-Wallis and χ 2 tests were used to compare median values and categorical data between prespecified groups. The statistical significance was set at α=0.05. Results The out-of-hospital group reported a more favorable response to time-sensitive stroke process metrics than the in-hospital group, as measured by median stroke team response time (15.0 vs 26.0 minutes; P ≤.0001) and median head computed tomography scan completion time (12.0 vs 41.0 minutes; P =.0001). There was no difference in the stroke alert time between the 2 groups (14.0 vs 8.0 minutes; P =.089). Longer hospital length of stay (4 vs 3 days; P =.004) and increased hospital mortality (19.3% vs 7.4%; P =.0032) were observed for the in-hospital group. Conclusions The key findings in this study were that time-sensitive stroke process metrics and stroke outcome measures were superior for the out-of-hospital groups compared with the in-hospital groups. Focusing on improving time-sensitive stroke process metrics may improve outcomes in the in-hospital stroke cohort.
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Chukwudelunzu et al. (2023) studied this question.
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