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August 16, 2021Frontiers in NeuroscienceOpen Access

Acupuncture With deqi Modulates the Hemodynamic Response and Functional Connectivity of the Prefrontal-Motor Cortical Network

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Why the study?

How the cortical network is modulated by acupuncture, particularly during acupuncture at the Hegu acupoint, remains largely unclear.

Does acupuncture manipulation at the Hegu acupoint modulate the hemodynamic response and functional connectivity of the prefrontal-motor cortical network in healthy volunteers?

Population

Twenty healthy subjects

Comparison

Acupuncture manipulation vs tactile controls and rest controls

Design

Multi-channel functional near-infrared spectroscopy physiological study

Authors

XSXiaopeng SiSXShaoxin XiangLZLudan Zhang

Discussion

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Overview

Supports neuromodulatory effects of acupuncture on prefrontal-motor networks in healthy volunteers; leaves open clinical translation pending controlled trials.

Structured PICO

Does acupuncture manipulation at the Hegu acupoint modulate the hemodynamic response and functional connectivity of the prefrontal-motor cortical network in healthy volunteers?

P
Population
20 healthy right-handed volunteers (mean age 23.9 ± 1.5 years, 12 males, 8 females), naive to acupuncture, with no history of mental illness or brain damage.
I
Intervention
Acupuncture manipulation at the Hegu acupoint (LI4) using the twirling method (90°-180° range, 2 Hz frequency) for 2 minutes.
C
Comparator
Pre- and post-manipulation tactile controls (needle inserted to a certain depth without twisting for 5 minutes) and pre- and post-acupuncture rest controls (5 minutes).
O
Outcome
Hemodynamic response (oxygenated hemoglobin [HbO] concentration) and functional connectivity of the prefrontal-motor cortical network measured by multi-channel functional near-infrared spectroscopy (fNIRS).surrogate

Acupuncture manipulation at the Hegu acupoint modulates a cooperative prefrontal-motor functional network, providing neuroimaging evidence for its central neuromodulatory effects.

Cite This Study

Si et al. (2021) studied this question.

synapsesocial.com/papers/6a82319bf2e4e6540e2a5030https://doi.org/10.3389/fnins.2021.693623
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