Why the study?
Are patients presenting for major reconstructive vascular surgery optimally managed with guideline-directed medical therapy?
Are patients presenting for major reconstructive vascular surgery optimally managed with guideline-directed medical therapy?
Pharmacologic risk factor modification in patients prior to major vascular surgery remains suboptimal despite established guideline recommendations.
Suboptimal preoperative GDMT persists in vascular surgery patients; leaves open whether targeted interventions improve adherence and outcomes.
BACKGROUND: Risk factor modification is important in patients with vascular disease. Guidelines suggest that this patient population benefits from a medical regimen of antiplatelets, statins, beta-blockers, and angiotensin-converting enzyme (ACE) inhibitors. MATERIALS AND METHODS: The medical regimen of consecutive patients who presented for major vascular surgery intervention over 18 months was examined. RESULTS: Of the 325 patients identified, 176 (54%) were on antiplatelet treatment, 197 (61%) were on a statin, 180 (55%) on beta-blockers, and 146 (54%) on ACE inhibitors. A high-risk subset of 94 smokers with known coronary artery disease, hypertension, and hyperlipidemia or diabetes was identified. In this subset, patients were more likely to be on pharmacologic risk factor modification. CONCLUSIONS: Despite recommendations, the pharmacologic risk factor modification of patients prior to vascular surgery remains suboptimal. Increased awareness of the problem and active participation of the vascular specialist are essential to improve compliance with established guidelines.
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Marshall et al. (2009) studied this question.
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