Why the study?
While perioperative goal-directed therapy reduces postoperative complications in high-risk patients, its effect across both high- and low-risk patients and different surgical procedures warranted evaluation.
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Population
High- and low-risk surgical patients
Comparison
Goal-directed therapy vs standard care across different surgical procedures
Design
Meta-analysis
Supports GDT to cut postoperative complications across risk strata and procedures; reinforces consensus while leaving low-risk and other surgeries open for confirmation.
Introduction: Goal directed therapy (GDT) is a method aiming at optimizing doses and timing of fluids, inotropes and vasopressors, through monitoring of cardiac output and other basic hemodynamic parameters. Several meta-analyses confirm that GDT can reduce postoperative complications in high risk patients, and a recent trial suggests its significant effect also in low-moderate risk patients. The aim of the present meta-analysis is to investigate the effect of GDT on postoperative complications, in both high and low risk patients. Moreover, we stratified the effect of GDT in different kind of surgical procedures.
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Giglio et al. (2019) studied this question.
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