Why the study?
Does pericardectomy and long-term antifungal therapy improve disease control in immunocompromised patients with Aspergillus pericarditis?
Does pericardectomy and long-term antifungal therapy improve disease control in immunocompromised patients with Aspergillus pericarditis?
Pericardectomy combined with long-term antifungal therapy can be an effective treatment strategy for Aspergillus pericarditis, achieving disease control without local relapse.
May support pericardectomy with prolonged antifungals for Aspergillus pericarditis; hypothesis-generating and requires prospective validation.
We report the case of an immunocompromised patient admitted for chest pain secondary to pericardial effusion. Pericardiocentesis liquid analysis revealed an Aspergillus pericarditis. Advanced multimodality imaging later revealed invasive aspergillosis. The patient was treated with pericardectomy and long-term antifungal therapy. Novel teaching points are as follows: Pericardectomy is an efficient treatment for Aspergillus pericarditis. Disease control can be obtained without local relapse with pericardectomy and long-term antifungal therapy.
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Guimaron et al. (2022) studied this question.
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