Transferrin-conjugated gold nanorods are used for efficient targeting, two-photon imaging, and photothermal therapy of cancer cells under both linearly and circularly polarized femtosecond illuminations. The results show that the effective laser energy threshold for therapy can be reduced to around 10 mJ cm−2, which is one order of magnitude lower than the medical safety standard level.
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Li et al. (2008) studied this question.
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