What question did this study set out to answer?

To assess whether body surface potential mapping can detect electrical activation abnormalities occurring during the mid and late phases of ventricular depolarization following acute anterior myocardial infarction.

December 1, 1976CirculationOpen Access

Anterior infarctional changes occurring during mid and late ventricular activation detectable by surface mapping techniques.

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Why the study?

Does body surface potential mapping detect mid and late ventricular activation abnormalities in patients with recent acute anterior myocardial infarction?

Population

26 patients with a recent acute anterior myocardial infarction and 30 normal subjects

Comparison

Body surface potential mapping vs Normal range established from the 30 normal…

Design

Case-control

Authors

NFNancy C. FlowersUniversity of Illinois Urbana-Champaign LHLeo G. HoranUniversity of Louisville JJJennifer JohnsonChildren's Advocacy Center

Discussion

Member takes

Implication

Body surface potential mapping may detect mid-late activation abnormalities missed by ECG after anterior MI; hypothesis-generating and requires prospective validation.

Key Points

To assess whether body surface potential mapping can detect electrical activation abnormalities occurring during the mid and late phases of ventricular depolarization following acute anterior myocardial infarction.
Measured body surface potential maps at 5 msec intervals across 142 recording sites in 30 normal subjects to establish reference voltage distributions (mean ± 2 SD).
Compared activation departure maps in 26 patients with recent acute anterior myocardial infarction against the normal reference standards to determine the location, duration, and timing of abnormalities.
Only 4 of 26 patients had potential departures confined to the early Q time zone, whereas 20 patients exhibited prominent positive and negative departures exceeding ± 2 SD well after 30 msec.
Two patients who had diagnostic Q waves upon initial hospitalization lost them prior to mapping but still demonstrated marked departure abnormalities between 30 and 60 msec after activation onset.
Electrical changes during the mid and late ventricular activation sequence were clearly displayed by body surface potential mapping despite being undetectable by standard electrocardiography or vectorcardiography.

Structured PICO

Does body surface potential mapping detect mid and late ventricular activation abnormalities in patients with recent acute anterior myocardial infarction?

Population

26 patients with a recent acute anterior myocardial infarction and 30 normal subjects

Intervention

Body surface potential mapping (142 recording sites at 5 msec intervals)

Comparator

Normal range established from the 30 normal subjects

Outcome

Departures from normal voltage distribution during ventricular activation (location, duration, and intensity)surrogate

Body surface potential mapping can detect mid and late ventricular activation abnormalities in patients with recent anterior myocardial infarction that are not detectable by conventional electrocardiography.

Cite This Study

Flowers et al. (1976) studied this question.

synapsesocial.com/papers/6a82479d477bdf2e97a20c05 https://doi.org/10.1161/01.cir.54.6.906

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Implication

Body surface potential mapping may detect mid-late activation abnormalities missed by ECG after anterior MI; hypothesis-generating and requires prospective validation.

Anterior infarctional changes occurring during mid and late ventricular activation detectable by surface mapping techniques.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Anterior infarctional changes occurring during mid and late ventricular activation detectable by surface mapping techniques.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider