Why the study?
Does prior treatment with PTCA compared to medical therapy alter the angiographic characteristics of culprit lesions that subsequently cause acute coronary syndrome?
Population
222 patients who had previously undergone coronary angiography and subsequently developed acute coronary…
Comparison
Percutaneous transluminal coronary angioplasty vs Medical treatment (n=127)
Design
Cohort
Follow-up
5 years
Authors
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Prior PTCA was associated with more ACS from insignificant stenoses yet lower AMI; leaves open whether it alters culprit progression pending randomized confirmation.
Does prior treatment with PTCA compared to medical therapy alter the angiographic characteristics of culprit lesions that subsequently cause acute coronary syndrome?
Acute coronary syndromes frequently develop from angiographically insignificant lesions, and prior PTCA may reduce the risk of high-grade stenoses progressing to occlusive lesions causing AMI.
Saito et al. (1998) studied this question.
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