Why the study?
Does the spread of native T1 values assessed with MRI identify cardiac involvement in patients with Fabry disease?
Does the spread of native T1 values assessed with MRI identify cardiac involvement in patients with Fabry disease?
Native T1 spread on MRI is a reproducible biomarker for cardiac involvement in Fabry disease, offering an alternative for patients unable to undergo late gadolinium enhancement imaging.
May offer alternative cardiac assessment in Fabry disease when gadolinium is contraindicated; leaves open prospective validation.
Increased native T1 spread is a reproducible imaging biomarker of cardiac involvement in Fabry disease and may be particularly useful in the evaluation of patients who cannot undergo late gadolinium enhancement imaging.
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Karur et al. (2020) studied this question.
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